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6-dihydro-2H-pyridin-5-yl]pyrazin-2-yl]benzamide
equivalent to the effect of used with 2 times doses of EKI-785 (40 mg/kg/day)
63(8):2352-62
InChiKey: GTTBEUCJPZQMDZ-HVTBMTIBSA-N
InChi: InChI=1S/C18H19N3O6S/c1-9(22)27-7-11-8-28-17-13(16(24)21(17)14(11)18(25)26)20-15(23)12(19)10-5-3-2-4-6-10/h2-6
PD-1/PD-L1-IN 3 ermine 6-dihydro-2H-pyridin-5-yl]pyrazin-2-yl]benzamidePD 1 PD L1 IN 3, a macrocyclic peptide, is a potent and selective inhibitor of the PD 1 PD L1 and CD80 PD L1 interactions extracted from patent WO2014151634A1, compound No. 1. PD 1 PD L1 IN 3 interferes with PD L1 binding to PD 1 and CD80 by binding to PD L1, with IC50s of 5. 60 nM and 7. 04 nM, respectively. PD 1 PD L1 IN 3 can be used for the research of various diseases, including cancer and infectious diseases. Product information CAS Number:
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