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with rapid clearance and barely measurable bioavailability
has minimum 32-fold selectivity against BRD9
Chemical Name: N-(trans-3-[5-[(1R)-1-hydroxyethyl]-1
Ki8751 (20 mg/kg) inhibits tumor growth
975 μg/mL
Pixantrone (dimaleate) Catalog No.:M9764-10 with rapid clearance and barelyPixantrone is a synthetic, noncardiotoxic aza anthracenedione analogue with potential antineoplastic activity. Pixantrone intercalates into DNA and induces topoisomerase II mediated DNA strand crosslinks, resulting in inhibition of DNA replication and tumor cell cytotoxicity. Pixantrone is a potentially more effective, less cardiotoxic alternative to doxorubicin for patients with aggressive non Hodgkin lymphoma (aNHL). Product information CAS Number:
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