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Formula: C20H22N2O5
with no effect on other mGluR subtypes
ZM306416 antagonizes the activity of KDR and Flt VEGF receptors with IC50 values of 100 nM and 2 μM
Applications of frontal affinity chromatography coupled to mass spectrometry in drug discovery
Analytical comparison of natural and pharmaceutical ventricular myosin activators
ML224 - CAS# 1338824-21-7 60328 Formula: C20H22N2O5ML224, also known as NCGC00242364 and ANTAG3, CAS No. 1338824 21 7, is a selective TSHR inverse agonist; inhibits TSH stimulated cAMP production with an IC50 = 2. 3 M. ML224 could be a useful tool for studying TSHR functions; it could also be a potential lead for development of drugs to treat TSHR mediated hyperthyroidism caused by constitutively activating mutations or stimulating auto antibodies associated with Graves disease. Product information