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3]thiazin-7a(7H)-yl)-4-fluorophenyl)-5-fluoropicolinamide hydrochloride
28(1):115228
Raf kinases are critical enzymes in the Ras/Raf/MEK/ERK signaling pathway and are frequently upregulated in neoplasms
InChi: InChI=1S/C41H71N3O8/c1-8-35-32(26-44-20-13-10-14-21-44)23-27(2)15-16-33(45)28(3)24-31(17-22-43-18-11-9-12-19-43)40(29(4)34(46)25-36(47)51-35)52-41-39(49)37(42(6)7)38(48)30(5)50-41/h15-16
when administered i
Taletrectinib Size:10mg solid 3]thiazin-7a(7H)-yl)-4-fluorophenyl)-5-fluoropicolinamide hydrochlorideTaletrectinib (DS 6051b, AB 106) is a new generation selective ROS1 NTRK inhibitor with ic50 of 0. 207 nM, 0. 622 nM, 2. 28 nM and 0. 980 nM for ROS1, NTRK1, NTRK2 and NTRK3, respectively. Product information CAS Number: 1505515 69 4 Molecular Weight: 551. 61 Formula: C29H34FN5O5 Synonym: DS 6051B adipate Chemical Name: 3 [4 [((2R) 2 Aminopropyl)oxy]phenyl] N [(1R) 1 (3 fluorophenyl)ethyl]imidazo[1, 2 b]pyridazin 6 amine monoadipate Smiles:
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