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Chymase-IN-1 10740 Semilicoisoflavone B reduces amyloid β

SKU: 83137101929

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Description

Semilicoisoflavone B reduces amyloid β (Aβ) secretion by inhibiting β-secretase-1 (BACE1) expression and activity

CAS Number: 2384184-44-3

Except for PDE4C2

and a panel of other serine/threonine kinases

30 min before LPS intravenous injection) significantly attenuates the increase in lung MPO activity induced by LPS in acute lung inflammation and it reduces the lung microvascular leakage from rats inflamed with LPS at the 4 h (32

Chymase-IN-1 10740 Semilicoisoflavone B reduces amyloid βChymase IN 1 is a potent, selective, orally active, nonpeptide inhibitor of human mast cell chymase with an IC50 of 29 nM. Product information CAS Number: 862090 74 2 Molecular Weight: 431. 83 Formula: C20H15ClNO4PS Chemical Name: [(5 chloro 1 benzothiophen 3 yl)[(naphthalen 2 yl)carbamoyl]methyl]phosphonic acid Smiles: OP(O)(=O)C(C1=CSC2=CC=C(Cl)C=C12)C(=O)NC1=CC2=CC=CC=C2C=C1 InChiKey: HUJXISJLAPAFBO UHFFFAOYSA N InChi: InChI=1S C20H15ClNO4PS c21 14

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