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22)5)26(4)13-11-20(28)15-19(26)16-24(25)29/h16-18
CAS Number: 105826-92-4
K562 (chronic myeloid leukemia)
83 mg/mL (37
and movements
GGTI-2418 14533 22)5)26(4)13-11-20(28)15-19(26)16-24(25)29/h16-18GGTI 2418 is a highly potent, competitive, and selective geranylgeranyltransferase I (GGTase I) inhibitor. GGTI 2418 inhibits GGTase I and FTase activities with IC50s of 9. 5 nM and 53 M, respectively. GGTI 2418 also increases p27(Kip1) and induces significant regression of breast tumors. Product information CAS Number: 501010 06 6 Molecular Weight: 441. 52 Formula: C23H31N5O4 Chemical Name: (2S) 2 {[(2S) 2 benzyl 4 [(5 methyl 1H imidazol 4 yl)methyl]
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