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PF-8380 exposures estimated by area under the curve are approximately proportional to dose and linear up to 100 mg/kg
Formula: C16H27N2O4P
159(2):508-11
When given intravenously
InChi: InChI=1S/C22H43N5O13/c23-2-1-8(29)20(36)27-7-3-6(25)18(39-22-16(34)15(33)13(31)9(4-24)37-22)17(35)19(7)40-21-14(32)11(26)12(30)10(5-28)38-21/h6-19
PLP (139-151) 19078 PF-8380 exposures estimated by areaPLP (139 151) is amino acid residue 139 to 151 of myelin proteolipid protein (PLP) used to induce experimental autoimmune encephalomyelitis (EAE). Product information CAS Number: 131334 43 5 Molecular Weight: 1537. 79 Formula: C72H104N20O16S Chemical Name: (3S) 3 {[(1S) 5 amino 1 {[(1S) 1 carboxy 2 phenylethyl]carbamoyl}pentyl]carbamoyl} 3 {[(2S) 1 [(2S) 2 {2 [(2S) 2 [(2S) 2 [(2S) 6 amino 2 {2 [(2S) 2 [(2R) 2 [(2S) 2 amino 3 (1H imidazol 5