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FPA-124 interacts with both the pleckstrin homology (PH) and the kinase domains of Akt
characterized
CAS Number: 356066-46-1
α-MSH modulates NFκB activation
Smiles: NC1C=CN([C@@H]2O[C@H](COP(O)(O)=O)[C@@H](O)[C@H]2O)C(=O)N=1
TBK1/IKKε-IN-4 ulfonate hydrate) FPA-124 interacts with both theTBK1 IKK IN 4 is a 6 aminopyrazolopyrimidine derivative and a potent, selective TBK1 and IKK inhibitor with IC50 values of 13 nM and 59 nM, respectively. TBK1 IKK IN 4 shows 100 to 1000 fold less activity against other protein kinases including PDK1, PI3K family members and mTOR. Product information CAS Number: 1381930 17 1 Molecular Weight: 533. 62 Formula: C28H35N7O4 Chemical Name: N {3,4 dimethoxy 5 [3 (4 methylpiperazin 1 yl)propoxy]phenyl} 1 (4
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