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Hck-IN-1 Size:Contact [email protected] for quotation From Streptomyces Griseolavendus

SKU: 57674354254

4.3
USD100.00 USD150.00

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Description

From Streptomyces Griseolavendus

InChi: InChI=1S/C22H22N8/c1-2-6-16-15(5-1)19(13-27-29-21-23-9-10-24-21)17-7-3-4-8-18(17)20(16)14-28-30-22-25-11-12-26-22/h1-8

Smiles: COC1=CC(O)=C2C(=O)C(=COC2=C1)C1C=CC(=CC=1)OC1OC(CO)C(O)C(O)C1O

also known as AEB-071

InChi: InChI=1S/C21H22FNO2

Hck-IN-1 Size:Contact [email protected] for quotation From Streptomyces GriseolavendusHck IN 1 (compound B9), a diphenylpyrazolo compound, is a selective Nef dependent Hck inhibitor with IC50s of 2. 8 M, >20 M for Nef: Hck complex and Hck, respectively. Hck IN 1 is a direct and wide HIV 1 Nef antagonists with an IC50 of 100 300 nM for wild type HIV 1 replication. Hck IN 1 binds pocket residue Asn126 and has anti retroviral activity. Product information CAS Number: 1473404 51 1 Molecular Weight: 402. 81 Formula: C16H11ClN6O3S Chemical

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