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PF-06372865 Catalog No.:M14974-2 AZD-9291 was approved in Nov

SKU: 55447374380

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Description

AZD-9291 was approved in Nov

InChi: InChI=1S/C22H44O7S/c23-22(24)10-12-26-14-16-28-18-20-29-19-17-27-15-13-25-11-8-6-4-2-1-3-5-7-9-21-30/h30H

Ponatinib (AP24534) potently inhibits native ABL (IC50: 0

Solubility: DMSO: 35 mg/mL(200

InChiKey: DFULPGUTXZTYKA-UHFFFAOYSA-N

PF-06372865 Catalog No.:M14974-2 AZD-9291 was approved in NovPF 06372865 is an orally active, 2 3 5 subtype selective GABAA positive allosteric modulator (PAM). PF 06372865 is a high affinity ligand at GABAA receptors containing 1 2 3 5 subunits (Kis of 2. 9 nM, 21 nM, 134 nM for 2, 1 PAM, 2 PAM, respectively), with low affinity for 4 6 subunits. PF 06372865 can across the blood brain barrier (BBB). PF 06372865 has anxiolytic activity and has the potential for epilepsy. Product information CAS Number: 1614245

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