CY-09 G11-azide but its efficacy declines as

but its efficacy declines as the disease progresses

CDK9-IN-7 also exhibits good inhibition potency with an IC50 value of 0

48 hours) decreases caspase 3 activation

P-Glycoprotein inhibitor and potent dopamine D2 receptor antagonist

44)/t21-/m1/s1

CY-09 G11-azide but its efficacy declines asCY 09 is a selective and direct NLRP3 inhibitor. CY 09 directly binds to the ATP binding motif of NLRP3 NACHT domain and inhibits NLRP3 ATPase activity, resulting in the suppression of NLRP3 inflammasome assembly and activation. Product information CAS Number: 1073612 91 5 Molecular Weight: 423. 43 Formula: C19H12F3NO3S2 Chemical Name: 4 {[(5Z) 4 oxo 2 sulfanylidene 3 {[3 (trifluoromethyl)phenyl]methyl} 1,3 thiazolidin 5 ylidene]methyl}benzoic acid