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InChi: InChI=1S/C22H23NO/c24-22-19-14-8-7-13-18(19)21(23-17-11-5-2-6-12-17)20(22)15-16-9-3-1-4-10-16/h1
and glutathione metabolism
Chemical Name: (R)-3-(3
Formula: C20H18FN5O
and augmented animal survival
PROTAC Bcl2 degrader-1 Catalog No.:M7983-2 InChi: InChI=1S/C22H23NO/c24-22-19-14-8-7-13-18(19)21(23-17-11-5-2-6-12-17)20(22)15-16-9-3-1-4-10-16/h1PROTAC Bcl2 degrader 1 (Compound C5) is a PROTAC, which potently and selectively induces the degradation of Bcl 2 (IC50, 4. 94 M; DC50, 3. 0 M) and Mcl 1 (IC50, 11. 81 M) by introducing the E3 ligase cereblon (CRBN) binding ligand pomalidomide to Mcl 1 Bcl 2 dual inhibitor Nap 1. Product information CAS Number: 2378801 85 3 Molecular Weight: 941. 84 Formula: C45H45BrN6O10S Chemical Name: N' (2 {8 [(4 bromophenyl)sulfanyl] 2, 4 dioxo 3 azatricyclo[7.