Guanfu base G 20308 MT-802 and SJF620 are potent

MT-802 and SJF620 are potent PROTAC BTK degraders with DC50s of 1 nM and 7

Smiles: CN(C)CCCN1C(=O)C2=CC(=CC=C2OC2=CC=CC=C12)[N+]([O-])=O

Erlotinib HCl completely prevents EGF-induced autophosphorylation of EGFR in human HN5 tumors growing as xenografts in athymic mice and of the hepatic EGFR of the treated mice

also used in the treatment of asthma via its inhibition of 5-lipoxygenase

4 μM in PU

Guanfu base G 20308 MT-802 and SJF620 are potentGuanfu base G is an antiarrhythmic alkaloid isolated from Aconitum coreanum. Guanfu base G inhibits HERG channel current with an IC50 of 17. 9 M. Product information CAS Number: 78969 72 9 Molecular Weight: 471. 54 Formula: C26H33NO7 Chemical Name: 10,19 bis(acetyloxy) 9 hydroxy 5 methyl 12 methylidene 7 azaheptacyclo[9. 6. 2. 0,. 0,. 0,. 0,. 0,]nonadecan 3 yl acetate Smiles: CC12CC(CC34C1C1CC56CC(=C)C(C(OC(C)=O)C53)C(OC(C)=O)C6(O)C4N1C2)OC(C)=O