Pay in 4 interest-free payments of $22.50 Learn more
Ships within 48 hours · Estimated delivery Sep 12 - Sep 17
84 L per h per kg body weight) and high oral bioavailability (37%)
and also carries the US NCI designation NSC-707389
3-dihydroxypropyl)acetamido]-2
2013 Jun 7
Isoprenaline (5 nM and 10 mM) increases cyclic AMP levels and this effect is potentiated by cilostamide (10 mM)
PND-1186 Catalog No.:M9572-2 84 L per h perPND 1186, also known as SR 2156 and VS 4718, is a potent FAK inhibitor with a 50% inhibitory concentration (IC50) of 1. 5 nM in vitro. PND 1186 has an IC50 of ~100 nM in breast carcinoma cells. Notably, 1. 0 M PND 1186 (>5 fold above IC50) had limited effects on cell proliferation. However, under non adherent conditions as spheroids and as colonies in soft agar, 0. 1 M PND 1186 blocked FAK and p130Cas tyrosine phosphorylation, promoted caspase 3
US$ 50000.00
US$ 2086.00
US$ 2237.50
US$ 1749.00
US$ 125000.00
US$ 7950.00
US$ 2659.00
US$ 92500.00
US$ 2454.50
US$ 82500.00
US$ 2397.50