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with a biochemical IC50 of 24 nM
135(5):1669-72
D-alpha-Hydroxyglutaric acid disodium
AZT can enhance CRISPR-mediated sequence-specific gene knockout via NHEJ in human induced pluripotent stem cells (iPSCs) and other cell types
It has no significant activity against a panel of 260 kinases at concentrations up to 10 µM
Purmorphamine - Hedgehog Agonist. CAS# 483367-10-8 66046 with a biochemical IC50 ofPurmorphamine, CAS No. 483367 10 8, is a Hedgehog agonist, which activates the Hedgehog pathway by targeting Smoothened. Purmorphamine induces osteogenesis by activation of the hedgehog signaling pathway. Purmorphamine increases DARPP 32 differentiation in human striatal neural stem cells through the Hedgehog pathway. Purmorphamine enhances osteogenic activity of human osteoblasts derived from bone marrow mesenchymal cells. Hedgehog (Hh) signaling is
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