It has one of the strongest colorless ETB effects in the game, giving you protection the turn you cast it, so you get a nice advantage even if you cast this card in the late game
But if you find yourself in a hand-based matchup, like a combo deck or a blue mirror, then Ego Drain seems like a big add for your Halo Forager package basically Faerie Fencing for non-creature decks
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An Isochron Scepter package that may include Orim's Chant, removal, tutors, counterspells, etc
This may be able to fit into some vampire builds considering vampires often have two or more creature types
Alternatively, if you like a more chaotic game, you can use this card to have players drop their best creatures early on and see what happens