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4-diazepan-1-yl)sulfonyl)isoquinoline dihydrochloride
Chemical Name: 4-[3-bromo-4-ethoxy-5-(4-methylbenzoyl)benzamido]benzoic acid
with pre- and post-treatment biopsies to evaluate for relevant molecular signatures
InChi: InChI=1S/C7H10N2OS/c1-2-3-5-4-6(10)9-7(11)8-5/h4H
Formula: C41H44ClFN6O7S2
Tamibarotene - CAS# 94497-51-5 Catalog No.:M10640-10 4-diazepan-1-yl)sulfonyl)isoquinoline dihydrochlorideTamibarotene, also known as SY 1425, is an orally active, synthetic retinoid, developed to overcome all trans retinoic acid (ATRA) resistance, with potential antineoplastic activity. As a specific retinoic acid receptor (RAR) alpha beta agonist, tamibarotene is approximately ten times more potent than ATRA in inducing cell differentiation and apoptosis in HL 60 (human promyelocytic leukemia) cell lines in vitro. Due to a lower affinity for cellular
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