Rilmenidine phosphate ydroabietic acid 7S)-3-(acetoxymethyl)-2-carboxy-8-oxo-5-thia-1-azabicyclo[4

7S)-3-(acetoxymethyl)-2-carboxy-8-oxo-5-thia-1-azabicyclo[4

6-diaminohexanoyl]amino]-3-methylpentanoyl]pyrrolidine-2-carbonyl]amino]-3-(4-hydroxyphenyl)propanoyl]amino]-3-methylpentanoyl]amino]-4-methylpentanoic acid

5 nM and 25 nM concentrations of ATN-224 for 24 h

Chemical Name: (2S)-3-methyl-2-(N-{[2'-(1H-1

α1βxγ2L and α4β2δ γ-Aminobutyric acid type A receptors (GABAARs) expressed in Xenopus oocytes

Rilmenidine phosphate ydroabietic acid 7S)-3-(acetoxymethyl)-2-carboxy-8-oxo-5-thia-1-azabicyclo[4Rilmenidine phosphate, an innovative antihypertensive agent, is an orally active, selective I1 imidazoline receptor agonist. Rilmenidine phosphate is an alpha 2 adrenoceptor agonist. Rilmenidine phosphate induces autophagy. Rilmenidine phosphate acts both centrally by reducing sympathetic overactivity and in the kidney by inhibiting the Na+ H+ antiport. Rilmenidine phosphate modulates proliferation and stimulates the proapoptotic protein Bax thus