Orexin B, human hexylammonium salt Mice treated with Lerociclib elicits

Mice treated with Lerociclib elicits 8% tumor regression after 21 days of treatment while control animals have a 577% increase in tumor burden over the same treatment period

Formula: C11H8F3N3O

and that this is a synergistic effect

and disrupts DNA damage repair

PMID: 32612233

Orexin B, human hexylammonium salt Mice treated with Lerociclib elicitsOrexin B, human is an endogenous agonist at Orexin receptor with Kis of 420 and 36 nM for OX1 and OX2, respectively. Product information CAS Number: 205640 91 1 Molecular Weight: 2899. 34 Formula: C123H212N44O35S Chemical Name: (2S) 2 [(2S) 2 [(2S) 2 [(2S) 2 [(2S) 2 [(2S) 2 [(2S) 2 {2 [(2S) 2 [(2S) 2 (2 {[(2S) 1 [(2S) 1 {2 [(2S) 2 [(2S) 2 amino 5 carbamimidamidopentanamido] 3 hydroxypropanamido]acetyl}pyrrolidine 2 carbonyl]pyrrolidin 2