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MMAF-OMe 18528 Smiles: CC1C=C2C(=C(C=1)OC)C1C=C(OC)C3C(C=1OC2=O)=C(C=CC=3O)C1OC(C)C(O)C(C)(O)C1O

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Description

Smiles: CC1C=C2C(=C(C=1)OC)C1C=C(OC)C3C(C=1OC2=O)=C(C=CC=3O)C1OC(C)C(O)C(C)(O)C1O

HA14-1 also markedly sustained TNF-alpha-mediated JNK activation

Formula: C7H12N2S2

Smiles: COC1C=C2C3=CC4=CC=C(OC)C(OC)=C4CN3CCC2=CC=1OC

5)1(6)7/h88-132

MMAF-OMe 18528 Smiles: CC1C=C2C(=C(C=1)OC)C1C=C(OC)C3C(C=1OC2=O)=C(C=CC=3O)C1OC(C)C(O)C(C)(O)C1OMMAF Ome, an antitubulin agent, belongs to ADC. MMAF Ome inhibits several tumor cell lines with IC50s of 0. 056 nM, 0. 166 nM, 0. 183 nM, and 0. 449 nM for MDAMB435 5T4, MDAMB361DYT2, MDAMB468, and Raji (5T4 ) cell lines, respectively. Product information CAS Number: 863971 12 4 Molecular Weight: 745. 99 Formula: C40H67N5O8 Chemical Name: methyl (2S) 2 [(2R) 2 [(R) [(2S) 1 [(3R,4S,5S) 4 [(2S) N,3 dimethyl 2 [(2S) 3 methyl 2

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