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(S)-CVN424 (example 149) inhibits cAMP activity with an IC50 of 58
InChi: InChI=1S/C13H9Cl2NO4/c1-19-13-7-9(3-4-11(13)16(17)18)20-12-5-2-8(14)6-10(12)15/h2-7H
associated with fumarase deficiency
Formula: C18H17N3O3S2
PF-622 showed highly selectivity for FAAH in relative to other serine hydrolases
Alcaftadine carboxylic acid Catalog No.:M34532-C (S)-CVN424 (example 149) inhibits cAMPAlcaftadine carboxylic acid is a broad spectrum antihistamine compound with high affinity for histamine H1 and H2 receptors and low affinity for H4 receptors. Alcaftadine carboxylic acid has also demonstrated effects on modulating immune cell recruitment and stabilizing mast cells. Alcaftadine carboxylic acid is more effective than placebo in preventing ocular itching associated with allergic conjunctivitis and is at least as effective as olopatadine
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